Soroprevalência de sífilis em gestantes admitidas na maternidade do Hospital Universitário de Dourados/MS

Abstract

Background: In Brazil, the number of syphilis cases reported in pregnant women has increased markedly in recent years. Thus, a cross-sectional study was conducted to identify the prevalence of Treponema pallidum infection and its associated factors in pregnant women visiting a public hospital in Dourados, Mato Grosso do Sul, Brazil. Methods: Based on a structured questionnaire, interviews were conducted for 661 pregnant women admitted for child birth, from January to June 2016. Blood samples were collected and analysed for serological diagnosis. Data of newborn were obtained by reviewing medical records. Univariable and multivariable regression analyses were performed to assess associations with syphilis. Results: The seroprevalence of syphilis in pregnant women was 4.4% (n = 29/661). Twenty-five newborns were reagent, and adverse outcomes were observed in 28% (n = 7/25) of newborns. Although 96.5% of women with syphilis received antenatal care, Venereal Disease Research Laboratory tests were performed in the first trimester for 47.6% women. Furthermore, women who received treatments in the third trimester (28.6%) were considered successfully treated at the time of delivery. In the multivariate analysis, the use of illicit drugs during pregnancy (OR: 13.3, 95% CI: 1.9–91.2) and the occurrence of abortions (OR: 3.7, 95% CI: 1.7–8) were found to be associated with syphilis. Conclusions: Our findings highlight that the poor quality of antenatal care services contributes to the high prevalence of syphilis, and there are social and behavioural risk factors associated with syphilis in pregnant women. However, future studies are needed to identify the limitations of clinical management and control services that are available to pregnant women with syphilis.