Formulação de máscara facial peel off com extrato etanólico de Cochlospermum regium com potencial antioxidante

Abstract

Currently, the number of consumers who opt for the selection of natural products that meet their needs, as well as sustainable guidelines, has been growing exponentially. From the perspective of cosmetics associated with skin care, facial masks stand out among other cosmetics due to their practicality and fast action. Among the types of facial masks, peel off is the most recommended for sensitive and dehydrated skin. Cochlospermum regium (Schrank) Pilger. is a relevant plant due to its active compounds and popular use for dermatological treatments, presenting itself as an option in the elaboration of natural cosmetics. In this context, the present work aimed to develop formulations of peel off facial masks with ethanolic foliar extract of C. regium (EEFC) and to evaluate its antimicrobial and antioxidant activity. The extract was incorporated into the base of a peel off facial mask already established in the literature. For the determination of their antimicrobial activity, the formulations were evaluated against Staphylococcus aureus (ATCC 25923) and Candida tropicalis (ATCC 750) by disk diffusion, well and by quantification of colonies. The antioxidant activity of the extract was evaluated by the free radical scavenging mechanisms 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2 – Azino-Bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and the formulation elaborated by the DPPH method, as well as a commercial mask associated with antioxidant action. The results indicated that the elaborated formulations did not maintain the antimicrobial activity performed by the extract. Regarding the antioxidant activity of the EEFC, it presented IC50 of 21.81 and 5.66 by the ABTS and DPPH radical capture method, respectively. The C. regium peel off facial mask formulation maintained the antioxidant activity of the extract (IC50 5.10) and the commercial facial mask did not demonstrate the antioxidant activity promised on the label (IC50 >250). These results on the elaborated formulation are unprecedented and promising for the use of C. regium extracts in cosmetic products.